https://doi.org/10.1140/epje/s10189-022-00184-4
Regular Article - Living Systems
A biaxial tensional model for early vertebrate morphogenesis
1
Laboratoire MSC, CNRS/Universit é de Paris Cité, UMR 7057, 10 rue Alice Domont et Ĺeonie Duquet, 75013, Paris, France
2
Laboratoire Mécanismes Adaptatifs et Evolution, UMR 7179 MNHN/CNRS, CP 55, 57 rue Cuvier, 75231, Paris Cedex 05, France
a
vincent.fleury@univ-paris-diderot.fr
Received:
29
January
2021
Accepted:
15
March
2022
Published online:
8
April
2022
We propose a simple biaxial tensional model which is able to reproduce at a qualitative level several aspects of early stages of vertebrate morphogenesis. The model is based on subsequent excitable contractions of an orthoradial and periclinal (radial) set of contracting lines, which generate first the basic embryonic pattern (a motile tube), and second the lateral orifices such as ears, eyes, mouth, gills, etc. An important aspect of the model is the self-arresting character of the process, akin to wound healing. At later stages, the biaxial lines may also work in extension, and this generates a developmental feedback which is quadratic with respect to curvature.
The original online version of this article was revised to add Figure 1b in the pdf version of the article.
Supplementary Information The online version contains supplementary material available at https://doi.org/10.1140/epje/s10189-022-00184-4.
A correction to this article is available online at https://doi.org/10.1140/epje/s10189-022-00199-x.
Copyright comment corrected publication 2022
© The Author(s) 2022. corrected publication 2022
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