Loops in DNA: An overview of experimental and theoretical approaches
Laboratoire de Physique Statistique de l'ENS, CNRS, 24 rue Lhomond, 75005, Paris, France
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Accepted: 2 February 2006
Published online: 23 March 2006
DNA loop formation plays a central role in many cellular processes. The aim of this paper is to present the state of the art and open problems regarding the experimental and theoretical approaches to DNA looping. A particular attention is devoted to the effects of the protein bridge size and of protein induced sharp DNA bending on DNA loop formation enhancement.
PACS: 87.14.Gg DNA, RNA – / 87.15.La Mechanical properties – / 87.15.He Dynamics and conformational changes –
© EDP Sciences, Società Italiana di Fisica and Springer-Verlag, 2006